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Piracetam Tablets manual
General name: Piracetam Tablets
English Name: Piracetam Tablets
Chinese phonetic alphabet: Bilaxitan Pian
The main ingredient of this product is piracetam. Its chemical name: 2 - oxy - 1 - pyrroliy alkyl acetamide chemical structure formula:

Molecular formula: C6H10N2O2
Molecular weight: 142.16
[character] this product is white
Indications are suitable for acute and chronic cerebrovascular disease, brain injury, various toxic encephalopathy and other causes of memory impairment and mild or moderate brain dysfunction. It can also be used for retardation of children's intelligence development
[Specification] 0.4g
Oral use. One 0.8 to 1.6g (2~4 tablets), 3 times a day, 4~8 weeks for a course of treatment. Half of children's consumption
[common adverse reaction] gastrointestinal adverse reactions are nausea, anorexia, abdominal discomfort, abdominal distension, abdominal pain and other symptoms, the severity and the dose is directly related to the. The side effects of the central nervous system include excitement, excitement, dizziness, headache, and insomnia, but the symptoms are mild and have nothing to do with the size of the dose. The symptoms disappeared after the drug was stopped. I see slight liver dysfunction, which shows a slight elevation of aminotransferase, but is not related to the dose of the drug.
[taboo] extrapyramidal diseases, Huntington disease is contraindicated in this product, so as not to aggravate the symptoms.
[cautions] patients with liver and kidney dysfunction should be carefully used and should be appropriately reduced.
[pregnant women and breast-feeding women] this product is easy to pass through the placental barrier, so pregnant women are forbidden; the indications for women in lactation are not clear.
Prohibition of newborn infants
[old medications] are not yet clear
[drug interaction] when combined with warfarin, this product can prolong the prothrombin time and induce inhibition of platelet aggregation. In patients receiving anticoagulant therapy, the application of piracetam should pay special attention to clotting time, prevent bleeding risk and adjust the dosage and usage of anticoagulant therapy.
[drug overdose] is not yet clear.
[pharmacologic toxicology] this product is an ameliorating drug for the brain metabolism, which belongs to the ring derivative of gamma aminobutyric acid. The effects of physical and chemical factors on brain damage caused by physical and chemical factors. It can promote the ATP in the brain, promote the synthesis of acetylcholine and enhance the conduction of nerve excitation, which can promote the metabolism of the brain. It can confront the brain damage caused by physical and chemical factors. It has an improved effect on the retrograde amnesia caused by hypoxia. It can enhance memory and improve learning ability. The acute toxicity test of animal experiments showed that the dose of gavage of mice was greater than 10g/kg, and no death was found. The median lethal dose of LD50 was 9.2g/kg. The subacute and chronic toxicological tests were not found to have any adverse effects on the growth and development of rats and dogs. There is no influence on the important organs and functions of blood, heart, liver, kidney, brain and other important visceral organs.
[pharmacokinetics] after taking this product, it quickly absorbed from the alimentary canal and entered the blood, and then reached the cerebrospinal fluid through the blood-brain barrier. The concentration of the cerebral cortex and olfactory bulb was higher than that of the brainstem. It is easy to pass through the placental barrier. After oral administration, the concentration of blood drug reached a peak in 30~45 minutes, the binding rate of plasma protein was 30%, and the half-life of T1/2 was 5~6 hours. The apparent distribution volume (Vd) was 0.6L/kg. Laci Staw can not be decomposed by the liver after oral administration and excreted in the form of urine and excrement in the form of the original form. The rate of renal clearance was 86ml/ minutes. The excretion of stool is about 1% - 2%.
(storage) shading, sealed and preserved
(packing) oral solid medicinal high density polyethylene bottles, 100 tablets per bottle
[period of validity] 36 months
The two part of the 2005 edition of the Chinese Pharmacopoeia
H23022866
[revision date] May 28, 2007
Enterprise name: Heilongjiang ha star Pharmaceutical Group Co., Ltd.
Address: Hegang Road, Gongnong District Sanjing
Postcode: 154101
Phone number: 0468-3122833 0468-3122885
Fax number: 0468-3122805
Web site: http://www.haxing.com
If there is any problem, contact with the production enterprise.

 


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